Nathaniel Appleton
- Born: 9 Dec 1693, Ipswich MA
- Marriage (1): Margaret Gibbs on 24 Mar 1720 in Cambridge MA
- Died: 9 Feb 1784, Cambridge MA
Events in his life were:

- Example: Desk and bookcase made by Christopher Townsend with silver hardware by Samuel Casey, circa 1745-1750, in Private Collection.
Nathaniel married Margaret Gibbs on 24 Mar 1720 in Cambridge MA. (Margaret Gibbs was born on 3 Jul 1699 in Watertown MA and died on 12 Jan 1771 in Cambridge MA.)
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